WebDec 8, 2016 · In order to find a potent and selective Shp2 inhibitor, we screened a diverse collection of the secondary metabolites from endophyte fungi using an in vitro enzyme assay, and finally identified a potent Shp2 inhibitor, HLP46 (demethylincisterol A 3) from Pestalotiopsis sp. HLP46 was reported to have anti-tumor and anti-inflammation activity ... WebJun 8, 2024 · One new dioxolanone derivative, guignardianone G (1) and twelve known compounds (2–13) were isolated from the 95 % ethanol extract of the plant endophytic fungus Phyllosticta capitalensis cultured in rice medium.Among these known compounds, isoaltenuene (3), brassicasterol (7), 5,6-epoxyergosterol (8), citreoanthrasteroid A (9), …
A novel biologically active xylaphenoside from the endophytic …
WebApr 18, 2024 · The fungus N. oryzae was isolated from marine sponge Haliclona sp. collected from Linshui area in the South China Sea. The fungus N. oryzae was grown on PDA at 25°C for 5 days, and then inoculated into 60 Erlenmeyer flasks containing 300 mL of Martin medium with 10% sea salt and incubated at 28°C for 4 weeks in static liquid … WebJan 18, 2011 · Compound 5 was identified as demethylincisterol A 3. Incisterol A 3, a highly degraded sterol, was first isolated from a marine sponge, Dictyonella incisa , and demethylincisterol A 3 (5) was prepared from ergosterol by photodegradation . Mansoor et al. isolated demethylincisterol A 3 (5) as a known compound from marine sponge … rob hornby facebook
demethylincisterol A3 C21H32O3 ChemSpider
WebThese findings indicate that demethylincisterol A 3 ( 1) is a natural antibiotic that may be used in the development of novel antibiotics against H. pylori. Keywords: Daedaleopsis confragosa; Polyporaceae; ergostane-type steroids; LC-MS/MS; anti- … Web2 days ago · Five previously undescribed specialized metabolites, including three 9,11-seco-pimarane diterpenoids, nodulisporenones A–C, and two androstane steroid… WebChemical examination of Chinese mangrove Rhizophora mucronata endophytic Pestalotiopsis sp., yielded 11 known metabolites with various structure types, including demethylincisterol A 3 ( 1 ), dankasterone B ( 2 ), (22 E, 24 R )-ergosta-7,9 (11), 22-triene-3 β, 5 α, 6 α -triol ( 3 ), ergosta-5,7,22-trien-3-ol ( 4 ), 5, 8-epidioxy-5, 8-ergosta-6, … rob horne arlington heights